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Home | Seminars and Symposia | Past seminars/symposia: Friday, May 9, 2008

Computational Prediction of Functional Modules and Their Regulatory Networks in Microbial Organisms

by

Ying Xu
Department of Biochemistry and Molecular Biology
University of Georgia

Friday, May 9, 2008
11:00 a.m. Seminar
12:00 p.m. Lunch

402 Walter Library

In this talk, I will present our recent work on computational prediction of biological networks in microbial organisms. I will discuss a number of computational techniques that we have been developing in the past few years, including prediction of genomic structures such as operons/regulons, prediction of cis regulatory elements and protein-DNA interactions, prediction of functional modules, and mapping of pathways/networks across microbial genomes, in support of our network prediction work. I will also discuss the challenging issues we are facing in terms of developing more effective computational tools and getting experimental data. I will then demonstrate how these tools have been used to elucidate a number of networks in cyanobacteria, including phosphorous assimilation network, carbon fixation network and nitrogen assimilation network and its crosstalk network with photosynthesis.